Learn more about the new Lexus IS 350 at Auto Loan Daily. Whether you're browsing or in full purchase mode our buyer's guide can help you get the information you want on each new car trim. The new Lexus IS 350 is available with a starting price of $40,320 but can reach prices of $42,780 based on various packages, options, and your trim selection. For those worried about fuel economy you should know that the base model new Lexus IS 350 gets 19 miles per gallon in the city and 27 miles per gallon when cruising on the highway. Select a trim below to learn more about the new IS 350 today.